HD-800
HD-800 is a tubulin inhibitor with an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. HD-800 can be used to generate a radioactive tracer [11C]HD-800, and [11C]HD-800 can penetrate the blood-brain barrier and be used for positron emission tomography (PET) in various neurological diseases.
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- CAS No.: 1204408-27-4
- 화학식: C15H15N3O2
- 분자량:269.30
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | GI50 |
10 nM
Compound: 3
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Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
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[PMID: 27213719] |
Chemical Information
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CAS No. 1204408-27-4
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분자량 269.30
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화학식 C15H15N3O2
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SMILES
N=1C=NC(=C2C1OC=C2C)N(C3=CC=C(OC)C=C3)C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HD-800 Related Classifications
HY-180347 Related Classifications
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