HD-800
HD-800 is a tubulin inhibitor with an IC50 of 4.3 nM and an EC50 for depolymerization of 24 nM. HD-800 can be used to generate a radioactive tracer [11C]HD-800, and [11C]HD-800 can penetrate the blood-brain barrier and be used for positron emission tomography (PET) in various neurological diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1204408-27-4
- 화학식: C15H15N3O2
- 분자량:269.30
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 786-0 | GI50 |
10 nM
Compound: 3
|
Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
Cytotoxicity against human 786-0 cells assessed as growth inhibition after 48 hrs by SRB assay
|
[PMID: 27213719] |
Chemical Information
-
CAS No. 1204408-27-4
-
분자량 269.30
-
화학식 C15H15N3O2
-
SMILES
N=1C=NC(=C2C1OC=C2C)N(C3=CC=C(OC)C=C3)C
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocol
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HD-800 Related Classifications
HY-180347 Related Classifications
Powered by Bioz