Insecticidal agent 37
Insecticidal agent 37 is an insecticide with activity against both nymph and adult stages of Aphis fabae. Insecticidal agent 37 exhibits strong binding affinity to the acetylcholine-binding protein of Aplysia californica via forming multiple hydrogen bonds and hydrophobic interactions with key residues.
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- 화학식: C21H12ClN3OS
- 분자량:389.86
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
In Vitro
Insecticidal agent 37 (compound 10b) binds strongly to the Aplysia californica acetylcholine-binding protein (PDB: 3SQ6) with a binding energy of −7.30 kcal/mol, forming multiple stabilizing hydrogen bonds and hydrophobic interactions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
Insecticidal agent 37 (10b) (five different concentrations; dipping method; single exposure; 10 s) exhibits high aphicidal activity against adult *Aphis fabae*, with an LC50 of 0.366 mg/L[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:nymph stage[1]
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Dosage:five different concentrations
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Administration:immersion; single exposure; 10 s
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Result:Exhibited a median lethal concentration (LC50) of 0.117 mg/L against Aphis fabae nymphs.
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Animal Model:adult stage[1]
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Dosage:five different concentrations
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Administration:immersion; single exposure; 10 s
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Result:Exhibited a median lethal concentration (LC50) of 0.366 mg/L against Aphis fabae adults.
Chemical Information
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분자량 389.86
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화학식 C21H12ClN3OS
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SMILES
N#CC1=C(OC2=C(C1C3=CC=C(C=C3)Cl)SC4=C2C=C5C=CC=CC5=N4)N
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)