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Cat. No.: HY-P6176

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JLB2-110c

JLB2-110c activates MCRs receptor (mMC4R EC₅₀ = 0.34 nM) and has a strong in vivo appetite suppressant effect.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3032608-72-0
화학식: C₇₁H₁₀₈N₂₈O₁₂
분자량:1545.80

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

JLB2-110c Chemical Structure

CAS No.: 3032608-72-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

JLB2-110c activates MCRs receptor (mMC4R EC₅₀ = 0.34 nM) and has a strong in vivo appetite suppressant effect^[1].

All Melanocortin Receptor Isoforms :

Chemical Information

CAS No. 3032608-72-0
분자량 1545.80
화학식 C₇₁H₁₀₈N₂₈O₁₂
Sequence

Cyclo(Pro-His-{d-Phe}-Arg-Trp-{Dap}-{Lys(Ac-Arg-Arg-Arg)}-{d-Pro})
Sequence Shortening

Cyclo(PH-{d-Phe}-RW-{Dap}-{Lys(Ac-RRR)}-{d-Pro})
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Ericson MD, et al. Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]. ACS Pharmacol Transl Sci. 2024 Apr 2;7(4):1114-1125. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

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Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
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JLB2-110c

All Melanocortin Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

JLB2-110c Related Classifications

HY-P6176 Related Classifications