Ledaborbactam
Based on 1 Customer Validation
Iedaborbactam (VNRX-5236), as a β-lactamase inhibitor (WO2015191907, Example 62), can be used for the research of bacterial infections.
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- Purity : 99.12%
- CAS No.: 1842397-36-7
- 화학식: C12H14BNO5
- 분자량:263.05
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보관:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Beta-lactamase Isoforms
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Biological Activity
제품 설명
IC50 & Target
beta-lactamase[1]
In Vitro
Iedaborbactam is a beta-lactamase inhibitor[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1842397-36-7
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Appearance Solid
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분자량 263.05
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화학식 C12H14BNO5
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Color White to off-white
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SMILES
OC(C1=C2C(C[C@@H](B(O2)O)NC(CC)=O)=CC=C1)=O
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Synonyms
VNRX-5236
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
용액&용해도
In Vitro:
DMSO : ≥ 100 mg/mL (380.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. WO2015191907
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8016 mL | 19.0078 mL | 38.0156 mL | 95.0390 mL |
| 5 mM | 0.7603 mL | 3.8016 mL | 7.6031 mL | 19.0078 mL | |
| 10 mM | 0.3802 mL | 1.9008 mL | 3.8016 mL | 9.5039 mL | |
| 15 mM | 0.2534 mL | 1.2672 mL | 2.5344 mL | 6.3359 mL | |
| 20 mM | 0.1901 mL | 0.9504 mL | 1.9008 mL | 4.7519 mL | |
| 25 mM | 0.1521 mL | 0.7603 mL | 1.5206 mL | 3.8016 mL | |
| 30 mM | 0.1267 mL | 0.6336 mL | 1.2672 mL | 3.1680 mL | |
| 40 mM | 0.0950 mL | 0.4752 mL | 0.9504 mL | 2.3760 mL | |
| 50 mM | 0.0760 mL | 0.3802 mL | 0.7603 mL | 1.9008 mL | |
| 60 mM | 0.0634 mL | 0.3168 mL | 0.6336 mL | 1.5840 mL | |
| 80 mM | 0.0475 mL | 0.2376 mL | 0.4752 mL | 1.1880 mL | |
| 100 mM | 0.0380 mL | 0.1901 mL | 0.3802 mL | 0.9504 mL |
Ledaborbactam Related Classifications
HY-132823 Related Classifications
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