LIG48
LIG48 is ROS1 kinase domain and its mutant (G2032R ROS1 kinase domain) inhibitor. LIG48 remains within the mutated and wild-type ROS1 kinase domains. LIG48 can be used for the study of non-small cell lung cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C22H25N7O4
- 분자량:451.48
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
LIG48 shows the highest binding affinity for wild-type ROS1 (-9.272 kcal/mol) and a binding affinity for G2032R mutant ROS1 of -8.9 kcal/mol[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 451.48
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화학식 C22H25N7O4
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SMILES
O=C(CN1C=CC(N)=NC1=O)N(C=C2C[C@@H](C(N3CCC[C@H]3C(N)=O)=O)N)C4=C2C=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LIG48 Related Classifications
HY-179527 Related Classifications
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