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Cat. No.: HY-144756

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LSD1-IN-15

LSD1-IN-15 (compound 1b) is a potent LSD1 inhibitor. LSD1-IN-15 can inhibit LSD1-CoREST, MAO-A and MAO-B, with IC₅₀ values of 0.149, 0.028, and 0.327 μM, respectively. LSD1-IN-15 displays cell growth arrest in prostate cancer LNCaP cells, with an IC₅₀ of 9.9 μM.

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CAS No.: 3033060-62-4
화학식: C₂₂H₂₀N₂O
분자량:328.41

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

LSD1-IN-15 Chemical Structure

CAS No.: 3033060-62-4

사이즈

가격

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수량

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

KDM1/LSD1

MAO-A

0.028 ± 0. μM (IC₅₀)

MAO-B

0.327 ± 0. μM (IC₅₀)

All Histone Demethylase Isoforms :

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

Chemical Information

CAS No. 3033060-62-4
분자량 328.41
화학식 C₂₂H₂₀N₂O
SMILES

NC1CC1C2=CC=C(C=C2)NC(C3=CC=CC(C4=CC=CC=C4)=C3)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fioravanti R, et al. Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity. J Enzyme Inhib Med Chem. 2022 Dec;37(1):973-985. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
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수량:
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LSD1-IN-15

All Histone Demethylase Isoforms

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

LSD1-IN-15 Related Classifications

HY-144756 Related Classifications