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Cat. No.: HY-182481

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MD-230254

MD-230254 is a reversible, competitive and selective inhibitor inhibitor of MAO-B with an IC₅₀ value of 1.8 nM. MD-230254 can be used for the study of MAO-B-related neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease.

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CAS No.: 147807-20-3
화학식: C₁₈H₁₅N₃O₃
분자량:321.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

MD-230254 Chemical Structure

CAS No.: 147807-20-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

MAO-B

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

In Vitro

MD-230254 potently and selectively inhibits MAO-B in rat liver mitochondria fraction with an IC₅₀ of 1.8 nM and a MAO-A/MAO-B selectivity ratio of >56,000^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 147807-20-3
분자량 321.33
화학식 C₁₈H₁₅N₃O₃
SMILES

N#CCCN1N=C(C2=CC=C(OCC3=CC=CC=C3)C=C2)OC1=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Lebreton L, et al. Selective and potent monoamine oxidase type B inhibitors: 2-substituted 5-aryltetrazole derivatives. J Med Chem. 1995;38(24):4786-4792. [Content Brief]

[2]. Yoshimoto M, et al. Synthesis and characterization of novel radiofluorinated probes for positron emission tomography imaging of monoamine oxidase B. J Labelled Comp Radiopharm. 2019;62(9):580-587. [Content Brief]

Calculators

몰농도 계산기

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Mass Mass

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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MD-230254

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MD-230254 Related Classifications

HY-182481 Related Classifications