Oregonin
Oregonin is a natural product.
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- CAS No.: 55303-93-0
- 화학식: C24H30O10
- 분자량:478.49
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HSC-T6 | IC50 |
>100 μM
Compound: 8
|
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
Antifibrotic activity against rat HSC-T6 cells assessed as inhibition of proliferation after 48 hrs by BrdU incorporation assay
|
[PMID: 21504848] |
| RAW264.7 | IC50 |
14.3 μM
Compound: 5
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 20 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 20 hrs by Griess assay
|
[PMID: 33422907] |
| RAW264.7 | IC50 |
16.7 μg/mL
Compound: 5
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced NO production incubated for 24 hrs by Griess assay
|
[PMID: 33422907] |
| RAW264.7 | IC50 |
20.7 μg/mL
Compound: 5
|
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis
Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of IFN-gamma and LPS-induced COX2 production preincubated for 2 hrs followed by IFN-gamma and LPS stimulation and measured after 16 hrs by spectrophotometric analysis
|
[PMID: 33422907] |
| RAW264.7 | IC50 |
21.1 μM
Compound: 5
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 0.5 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
|
[PMID: 33422907] |
| RAW264.7 | IC50 |
9.7 μM
Compound: 5
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production preincubated for 1 hrs followed by LPS stimulation and measured after 24 hrs by Griess reagent based analysis
|
[PMID: 33422907] |
Chemical Information
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CAS No. 55303-93-0
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Appearance Solid
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분자량 478.49
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화학식 C24H30O10
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Color White to off-white
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SMILES
OC(C=C1CC[C@@H](CC(CCC2=CC(O)=C(C=C2)O)=O)O[C@H]3[C@@H]([C@H]([C@@H](CO3)O)O)O)=C(C=C1)O
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
순도&문서
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)