PF-06282999 (Standard)
PF-06282999 (Standard) is the analytical standard of PF-06282999. This product is intended for research and analytical applications. PF-06282999 is a potent and selective myeloperoxidase inhibitor which is potential useful for the treatment of cardiovascular diseases.
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- CAS No.: 1435467-37-0
- 화학식: C13H12ClN3O3S
- 분자량:325.77
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1435467-37-0
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분자량 325.77
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화학식 C13H12ClN3O3S
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SMILES
O=C(N)CN(C(C1=CC(Cl)=CC=C1OC)=C2)C(NC2=O)=S
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Dong JQ, et al. Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans. Drug Metab Dispos. 2016 Feb;44(2):209-19. [Content Brief]
[2]. Ruggeri RB, et al. Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases. J Med Chem. 20 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)