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Cat. No.: HY-100601

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PK7242

PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In cancer cells carrying the Y220C mutant, PK7242 binds to the p53-Y220C core domain and induces growth inhibition, cell-cycle arrest, and apoptosis.

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CAS No.: 1446352-68-6
화학식: C₁₇H₁₉FN₄
분자량:298.36

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

PK7242 Chemical Structure

CAS No.: 1446352-68-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 1446352-68-6
분자량 298.36
화학식 C₁₇H₁₉FN₄
SMILES

CN(C)CCN1N=C(N2C=CC=C2)C(C3=CC=C(F)C=C3)=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu, X., Wilcken, R., Joerger, A.C., et al. Small molecule induced reactivation of mutant p53 in cancer cells. Nucleic Acids Res. 41(12), 6034-6044 (2013). [Content Brief]

Calculators

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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