R-87366
R-87366 is a water-soluble human immunodeficiency virus (HIV) protease inhibitor. R-87366 has potent inhibitory for HIV protease with a Ki value of 11 nM. R-87366 can be used for the research of anti-human immunodeficiency virus (HIV).
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- CAS No.: 144779-91-9
- 화학식: C32H39N7O6
- 분자량:617.70
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Ki: 11 nM (HIV protease)[1].
IC90: 0.5 μM (HIV-1IIIB acutely infected cells)[1]
R-87366 has potent inhibitory for human immunodeficiency virus protease with a Ki value of 11 nM[1].
R-87366 has activity for HIV-1IIIB acutely infected cells with an IC90 value of 0.5 μM[1].
R-87366 has moderate water-solubility[1].
R-87366 (0.25 μM; 0.5 μM) also has active in chronically infected Molt-4/HIV-1IIIB cells, and inhibits the proteolytic processing of p55 into p17[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 144779-91-9
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분자량 617.70
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화학식 C32H39N7O6
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SMILES
O=C(N(CCC1)[C@@H]1C(NC(C)(C)C)=O)[C@@H](O)[C@@H](NC([C@H](CC(N)=O)NC(C2=CN=C3C(C=CC=C3)=N2)=O)=O)CC4=CC=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
R-87366 Related Classifications
HY-19232 Related Classifications
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