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Cat. No.: HY-111772AR

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(R)-Elexacaftor (Standard)

Name: (R)-Elexacaftor (Standard)
Brand: MedChemExpress
SKU: HY-111772AR
Availability: PreOrder

(Synonyms: (R)-VX-445 (Standard))

(R)-Elexacaftor (Standard) is the analytical standard of (R)-Elexacaftor (HY-111772A). This product is intended for research and analytical applications. (R)-Elexacaftor is an enantiomer of Elexacaftor (HY-111772). (R)-Elexacaftor is the Compound 37 from patent WO2018107100A1. (R)-Elexacaftor is a modulator of cystic fibrosis transmembrane conductance regulator (CFTR), the EC₅₀ for CFTR dF508 is 0.29 uM.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2229860-99-3
화학식: C₂₆H₃₄F₃N₇O₄S
분자량:597.65

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

(R)-Elexacaftor (Standard) Chemical Structure

CAS No.: 2229860-99-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 2229860-99-3
분자량 597.65
화학식 C₂₆H₃₄F₃N₇O₄S
SMILES

CC1(C)C[C@@H](C)CN1C2=C(C(NS(C3=CN(C)N=C3C)(=O)=O)=O)C=CC(N4C=CC(OCC(C)(C(F)(F)F)C)=N4)=N2
Synonyms

(R)-VX-445 (Standard)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator. WO2018107100A1

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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