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S58 aptamer

S58 aptamer is a ssDNA aptamer targeting transforming growth factor-beta receptor II (TGF-β RII). S58 aptamer inhibits the TGF-β RII interaction with TGF-β. S58 aptamer effectively improves glaucoma filtration surgery (GFS) surgical outcomes by activating the intracellular antioxidant defense PI3K/Akt/Nrf2 signaling pathway.

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  • S58 aptamer Chemical Structure
    S58 aptamer Chemical Structure
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All TGF-β Receptor Isoforms

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  • S58 aptamer Chemical Structure
    S58 aptamer Chemical Structure 5'-ACATTGCTGCGTGATCGCCTCACATGGGTTTGTCTGGTCGATTTGGAGGTGGTGGGTGGC-3'
    1/16
  • 5'-ACATTGCTGCGTGATCGCCTCACATGGGTTTGTCTGGTCGATTTGGAGGTGGTGGGTGGC-3'