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Cat. No.: HY-117896

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SC-50605

SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..

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CAS No.: 138828-39-4
화학식: C₃₀H₃₅NO₆S
분자량:537.67

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

SC-50605 Chemical Structure

CAS No.: 138828-39-4

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

LTB4^[1]

All Leukotriene Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HL-60	IC₅₀	660 nM Compound: 35	Inhibitory activity against LTB4 production in HL60s. Inhibitory activity against LTB4 production in HL60s.	[PMID: 7699700]
HL-60	IC₅₀	928 nM Compound: 35	Inhibitory activity against PGE-2 production in HL60s. Inhibitory activity against PGE-2 production in HL60s.	[PMID: 7699700]

Chemical Information

CAS No. 138828-39-4
분자량 537.67
화학식 C₃₀H₃₅NO₆S
SMILES

O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. LEUKOTRIENE B4-INDUCED GRANULOCYTE TRAFFICKING IN GUINEA PIG DERMIS Effect of Second-Generation Leukotriene B 4 Receptor Antagonists, SC-50605 and SC-51146

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

SC-50605

All Leukotriene Receptor Isoforms

Biological Activity

제품 설명

IC50 & Target

Cellular Effect

Chemical Information

순도&문서

References

Calculators

Help & FAQs

SC-50605 Related Classifications

HY-117896 Related Classifications

Bioz

Keywords

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