Sofetabart
Based on 1 Customer Validation
Sofetabart (LY-4170156 Antibody) is a humanized IgG1 antibody that specifically targets folate receptor α (FRα). Sofetabart can be used to synthesize the antibody-drug conjugate (ADC) Sofetabart mipitecan. Sofetabart is applicable to research related to advanced ovarian cancer, platinum-resistant epithelial ovarian cancer, fallopian tube cancer or primary peritoneal cancer, as well as platinum-sensitive ovarian cancer.
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- Purity : 98.00%
- CAS No.: 3066905-22-1
- 분자량:145.23 kDa
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보관:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
제품 설명
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
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FR-α |
In Vitro
Gene ID
Accession
Target
FOLR1/FRA
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
신청
ELISA, FACS, Functional assay
Verified Bioactivity
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Loaded Sofetabart on ProA biosensor, can bind FOLR1 Protein, Human (HEK293, HY-P70296) with an affinity constant of 2.087E-08 M as determined in BLI assay.
Chemical Information
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CAS No. 3066905-22-1
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분자량 145.23 kDa
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Synonyms
LY-4170156 Antibody; MBK-103 Antibody
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선적
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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Data Sheet (260 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- Sofetabart
- 3066905-22-1
- LY-4170156 Antibody
- MBK-103 Antibody
- ADC Antibodies
- Folate Receptor (FR)
- topoisomerase-I inhibitor
- topoisomerase 1 inhibitor
- folate receptor alpha
- platinum-resistant epithelial ovarian cancer
- fallopian tube cancer
- FRα-expressing cells
- primary peritoneal cancer
- cancer cell
- advanced ovarian cancer
- platinum-sensitive ovarian cancer
- Inhibitor
- inhibitor
- inhibit