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United States

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Cat. No.: HY-151554

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SQ-3

SQ-3 is a quinoline analogue, displays moderate selectivity for α-syn aggregates (K_i=39.3 nM) over β-amyloid (Aβ) aggregates (K_i=230 nM). [¹⁸F]SQ3 has basic properties as a lead compound for the development of a useful α-syn imaging probe.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

화학식: C₂₁H₂₁FN₂O
분자량:336.40

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

SQ-3 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

In Vivo

SQ-3 ([¹⁸F]SQ3) exhibits high uptake (2.08% ID/g at 2 min after intravenous injection) into a normal mouse brain^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

분자량 336.40
화학식 C₂₁H₂₁FN₂O
SMILES

CN(C)C1=CC=C(/C=C/C2=NC3=CC(OCCF)=CC=C3C=C2)C=C1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Nakagawa K, et al. Structure-Activity Relationships of Styrylquinoline and Styrylquinoxaline Derivatives as α-Synuclein Imaging Probes. ACS Med Chem Lett. 2022 Sep 26;13(10):1598-1605. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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