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Cat. No.: HY-189706

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Stafori-2

Stafori-2 is a selective STAT4 SH2 domain inhibitor. Stafori-2 binds to the STAT4 Src homology 2 (SH2) domain, blocking protein-protein interactions, with a human K_i value of 0.18 μM. Stafori-2 can be used in research related to autoimmune diseases such as multiple sclerosis, rheumatoid arthritis, and type 1 diabetes.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 3128949-21-0
화학식: C₁₁H₁₀FO₄PS
분자량:288.23

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Stafori-2 Chemical Structure

CAS No.: 3128949-21-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
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Calculators
Help & FAQs
Classifications
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Biological Activity

제품 설명

IC₅₀ & Target

^[1]

STAT4

0.18 μM (Ki)

STAT4

3.1 μM (Kd)

All STAT Isoforms :

In Vitro

Stafori-2 exhibits STAT4 inhibitory activity with a K_i of 0.18 μM and shows good selectivity over other STAT proteins^[1].
Stafori-2 binds to STAT4 with a K_d of 3.1 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 3128949-21-0
분자량 288.23
화학식 C₁₁H₁₀FO₄PS
SMILES

O=P(O)(OC1=C(F)C=C(C2=CSC(C)=C2)C=C1)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Brovchenko N, et al. Biaryl Phosphate-Based Inhibitors of the Transcription Factor STAT4. ChemMedChem. 2025 Nov 06;20(21):e202500672.

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

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Stafori-2

All STAT Isoforms

Biological Activity

제품 설명

IC50 & Target

In Vitro

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Stafori-2 Related Classifications

HY-189706 Related Classifications

Bioz

Keywords

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