TAC 363
TAC 363 is a selective tachykinin NK-2 receptor antagonist. TAC 363 shows a rightward shift in the contractile response curve induced by Neurokinin A (HY-P0197) with a pA2 of 9.82. TAC 363 has a weak antagonistic effect on NK-1 receptors. TAC 363 can inhibit Neurokinin A-induced bronchoconstriction in guinea pigs with an ED50 of 0.3 mg/kg. TAC 363 can be used for the research of bronchial asthma.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 172081-08-2
- 화학식: C38H48N8O6
- 분자량:712.84
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
|
Tachykinin NK2 Receptor 9.82 (pA2) |
Chemical Information
-
CAS No. 172081-08-2
-
분자량 712.84
-
화학식 C38H48N8O6
-
SMILES
O=C(NCCOCC1=CC=CC=C1)N(CC2=CC=CC=C2)NC([C@@H](NC([C@H](CCC(N)=O)NC(NC(C)(C)C)=O)=O)CC3=CNC4=CC=CC=C34)=O
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz