Treprostinil-d9
Based on 1 Customer Validation
Treprostinil-d9 (UT-15-d9) is the deuterium-labeled Treprostinil (HY-100441). Treprostinil (UT-15) is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.79%
- CAS No.: 2747918-14-3
- 화학식: C23H25D9O5
- 분자량:399.57
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
EC50: 0.6±0.1 nM (DP1), 6.2±1.2 nM (EP2)[1]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2747918-14-3
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Unlabeled Cas 81846-19-7
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Appearance Solid
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분자량 399.57
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화학식 C23H25D9O5
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Color White to off-white
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SMILES
OC(COC1=CC=CC2=C1C[C@]([H])([C@@]3(C2)[H])C[C@H]([C@@H]3CC[C@H](CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])O)O)=O
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Synonyms
UT-15-d9
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 125 mg/mL (312.84 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5027 mL | 12.5135 mL | 25.0269 mL | 62.5673 mL |
| 5 mM | 0.5005 mL | 2.5027 mL | 5.0054 mL | 12.5135 mL | |
| 10 mM | 0.2503 mL | 1.2513 mL | 2.5027 mL | 6.2567 mL | |
| 15 mM | 0.1668 mL | 0.8342 mL | 1.6685 mL | 4.1712 mL | |
| 20 mM | 0.1251 mL | 0.6257 mL | 1.2513 mL | 3.1284 mL | |
| 25 mM | 0.1001 mL | 0.5005 mL | 1.0011 mL | 2.5027 mL | |
| 30 mM | 0.0834 mL | 0.4171 mL | 0.8342 mL | 2.0856 mL | |
| 40 mM | 0.0626 mL | 0.3128 mL | 0.6257 mL | 1.5642 mL | |
| 50 mM | 0.0501 mL | 0.2503 mL | 0.5005 mL | 1.2513 mL | |
| 60 mM | 0.0417 mL | 0.2086 mL | 0.4171 mL | 1.0428 mL | |
| 80 mM | 0.0313 mL | 0.1564 mL | 0.3128 mL | 0.7821 mL | |
| 100 mM | 0.0250 mL | 0.1251 mL | 0.2503 mL | 0.6257 mL |
Treprostinil-d9 Related Classifications
HY-100441S2 Related Classifications
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