Tridecanedioic acid
Based on 1 Customer Validation
Tridecanedioic acid (Brassylic Acid) is a long-chain fatty acid and an endogenous serum metabolite. Tridecanedioic acid is positively correlated with the intestinal genus Tuzzerella in non-alcoholic steatohepatitis (NASH) mice fed a MCD diet. Tridecanedioic acid accumulates at high levels in Brassica napus germplasm tolerant to Plutella xylostella (diamondback moth), thereby participating in plant defense. Tridecanedioic acid can be used in studies related to Plutella xylostella infestation.
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- Purity: 99.93%
- CAS No.: 505-52-2
- 화학식: C13H24O4
- 분자량:244.33
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-128421R
Tridecanedioic acid (Standard) -
HY-W012241
Dodecanedioic acid -
HY-B0704
Azelaic acid -
HY-W014787
Decanedioic acid -
HY-W008820
Glutaric acid -
HY-W012241R
Dodecanedioic acid (Standard) -
HY-Y1139
Pimelic acid -
HY-W015300
Suberic acid -
HY-W018161
Hexadecanedioic acid -
HY-W008820R
Glutaric acid (Standard) -
HY-B0704R
Azelaic acid (Standard) -
HY-W011636
Pentadecanedioic acid
All Endogenous Metabolite Isoforms
More
Biological Activity
제품 설명
IC50 & Target
[1]|
Human Endogenous Metabolite |
In Vitro
Tridecanedioic acid accumulates significantly in tolerant Brassica napus varieties but remains at low levels in susceptible varieties, and plays an important role in the defense response against Plutella xylostella infestation[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 505-52-2
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Appearance Solid
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분자량 244.33
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화학식 C13H24O4
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Color White to off-white
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SMILES
O=C(O)CCCCCCCCCCCC(O)=O
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Synonyms
Brassylic Acid
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 100 mg/mL (409.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 2.5 mg/mL (10.23 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
순도&문서
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0928 mL | 20.4641 mL | 40.9283 mL | 102.3206 mL |
| 5 mM | 0.8186 mL | 4.0928 mL | 8.1857 mL | 20.4641 mL | |
| 10 mM | 0.4093 mL | 2.0464 mL | 4.0928 mL | 10.2321 mL | |
| 15 mM | 0.2729 mL | 1.3643 mL | 2.7286 mL | 6.8214 mL | |
| 20 mM | 0.2046 mL | 1.0232 mL | 2.0464 mL | 5.1160 mL | |
| 25 mM | 0.1637 mL | 0.8186 mL | 1.6371 mL | 4.0928 mL | |
| 30 mM | 0.1364 mL | 0.6821 mL | 1.3643 mL | 3.4107 mL | |
| 40 mM | 0.1023 mL | 0.5116 mL | 1.0232 mL | 2.5580 mL | |
| 50 mM | 0.0819 mL | 0.4093 mL | 0.8186 mL | 2.0464 mL | |
| 60 mM | 0.0682 mL | 0.3411 mL | 0.6821 mL | 1.7053 mL | |
| 80 mM | 0.0512 mL | 0.2558 mL | 0.5116 mL | 1.2790 mL | |
| 100 mM | 0.0409 mL | 0.2046 mL | 0.4093 mL | 1.0232 mL |
Tridecanedioic acid Related Classifications
HY-128421 Related Classifications
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