Variotin
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus.
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- CAS No.: 19504-77-9
- 화학식: C17H25NO3
- 분자량:291.39
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MOLT-4 | IC50 |
>200 μM
Compound: 1
|
Inhibition of DNA polymerase delta isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
Inhibition of DNA polymerase delta isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
|
[PMID: 24411199] |
| MOLT-4 | IC50 |
>200 μM
Compound: 1
|
Inhibition of DNA polymerase epsilon isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
Inhibition of DNA polymerase epsilon isolated from human MOLT4 cells assessed as inhibition of incorporation of dTTP into poly(dA)/oligo(dT)18 after 60 mins
|
[PMID: 24411199] |
Chemical Information
-
CAS No. 19504-77-9
-
분자량 291.39
-
화학식 C17H25NO3
-
SMILES
O=C1N(C(/C=C/C=C/C(C)=C/[C@H](O)CCCC)=O)CCC1
-
Structure Classification
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Initial Source
Paecilomyces varioti Bainer var.
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)