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Cat. No.: HY-P10332

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WL 47 dimer

WL 47 dimer (ligand 1) is a caveolin-1 (CAV-1) ligand with high affinity, selectivity and oligomer dissociation activity. WL 47 dimer simultaneously occupies two binding sites of CAV-1, inducing the dissociation of oligomers. WL 47 dimer has 7500-fold improved affinity compared to its T20 parent ligand and an 80% decrease in sequence length. WL 47 dimer can be used to permit targeted study of CAV-1 function.

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화학식: C₈₀H₁₃₀N₂₄O₁₈S₄
분자량:1844.30

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

WL 47 dimer Chemical Structure

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

분자량 1844.30
화학식 C₈₀H₁₃₀N₂₄O₁₈S₄
Sequence

Chain1: Cys-Ser-Trp-Met-Arg-Leu-Lys Chain2: Cys-Ser-Trp-Met-Arg-Leu-Lys (Disulfide bridge: Chain1 Cys1-Chain2 Cys1)
Sequence Shortening

Chain1: CSWMRLK Chain2: CSWMRLK (Disulfide bridge: Chain1 Cys1-Chain2 Cys1)
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gilliam A J H, et al. Affinity-guided design of caveolin-1 ligands for deoligomerization[J]. Journal of medicinal chemistry, 2016, 59(8): 4019-4025. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) Concentration _(start)

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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