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Cat. No.: HY-120376

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XZH-5

XZH-5 inhibits the phosphorylation of STAT3 and results in the induction of apoptosis and reduction of colony forming ability.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1360562-98-6
화학식: C₂₂H₂₅F₆N₅O₄
분자량:537.46

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

XZH-5 Chemical Structure

CAS No.: 1360562-98-6

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

XZH-5 inhibits the phosphorylation of STAT3 and results in the induction of apoptosis and reduction of colony forming ability^[1].

All STAT Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HPAC	IC₅₀	17.4 μM Compound: 1a	Cytotoxicity against human HPAC cells after 72 hrs by MTT assay Cytotoxicity against human HPAC cells after 72 hrs by MTT assay	[PMID: 25698618]
MDA-MB-231	IC₅₀	15.5 μM Compound: 1a	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 25698618]
PANC-1	IC₅₀	24.7 μM Compound: 1a	Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay	[PMID: 25698618]
SW1990	IC₅₀	17.9 μM Compound: 1a	Cytotoxicity against human SW1990 cells after 72 hrs by MTT assay Cytotoxicity against human SW1990 cells after 72 hrs by MTT assay	[PMID: 25698618]

Chemical Information

CAS No. 1360562-98-6
분자량 537.46
화학식 C₂₂H₂₅F₆N₅O₄
SMILES

O=C(OC)[C@H](CC1=CN(C)C=N1)NC([C@H](C(C)C)NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li Chenglong, et al. Compound XZH-5 inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human hepatocellular carcinoma cells. World Intellectual Property Organization, WO2012078982 A2 2012-06-14

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Other size

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Amount: USD 0.00

Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

XZH-5

All STAT Isoforms