Z-4105
Z-4105 is an orally active nootropic agent. Z-4105 reverses the amnesic effects of electroconvulsive shock (ECS) and methylazoxymethanol acetate (MAM), and improves learning and memory functions. Z-4105 enhances the activity of the brain cholinergic system without affecting other neurotransmitter systems. Z-4105 significantly alleviates neuropathic pain in rats. Z-4105 can be used in the research of neuropathic pain and brain dysfunction.
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- CAS No.: 119737-52-9
- 화학식: C9H12N2O4
- 분자량:212.20
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Wistar (male, chronic constrictive injury of the sciatic nerve model); Wistar (male, spinal nerve ligation model)[1]
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Dosage:3 mg/kg; 30 mg/kg; 300 mg/kg
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Administration:p.o.; single dose
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Result:Reduced mechanical allodynia in a dose-dependent manner.
Produced statistically significant antiallodinic effect starting at 3 mg/kg, which persisted up to 6 hours post-treatment.
Reduced mechanical allodynia in a dose-dependent manner.
Produced statistically significant antiallodinic effect starting at 3 mg/kg, which persisted up to 6 hours post-treatment.
Chemical Information
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CAS No. 119737-52-9
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분자량 212.20
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화학식 C9H12N2O4
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SMILES
O=C(CCCNC(C1=CC(C)=NO1)=O)O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)