2. PROTAC MAPK/ERK Pathway GPCR/G Protein
  3. Ligands for Target Protein for PROTAC Ras
  4. KRAS G12D ligand-3

KRAS G12D ligand-3 is a KRAS G12D PROTAC ligand. KRAS G12D ligand-3 can be conjugated with E3 ligase Ligand (HY-170348) and linke (HY-W895436) to synthesize KRAS G12D PROTAC degrader MS243 (HY-181728). MS243 can be used for cancer research.

For research use only. We do not sell to patients.

KRAS G12D ligand-3

KRAS G12D ligand-3 Chemical Structure

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KRAS G12D ligand-3 Related Antibodies

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Description

KRAS G12D ligand-3 is a KRAS G12D PROTAC ligand. KRAS G12D ligand-3 can be conjugated with E3 ligase Ligand (HY-170348) and linke (HY-W895436) to synthesize KRAS G12D PROTAC degrader MS243 (HY-181728). MS243 can be used for cancer research[1].

IC50 & Target

KRas G12D

 

Molecular Weight

614.64

Formula

C33H32F2N6O4
SMILES

FC(C=C1)=C(C#C)C(C1=CC(O)=C2)=C2C3=NC=C4C(N=C(OC[C@H]5N(CCC(O)=O)CCC5)N=C4N6C[C@H]7N[C@H](CC7)C6)=C3F
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS G12D ligand-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12D ligand-3Ligands for Target Protein for PROTACRasTarget Protein-binding MoietyInhibitorinhibitorinhibit

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