L-Lysine orotate
Based on 7 publication(s) in Google Scholar
L-Lysine orotate is a salt of L-lysine and orotic acid that can potentiate the toxicity of an extract of the mushroom Amanita phalloides.
For research use only. We do not sell to patients.
- CAS No.: 28003-86-3
- Formula: C11H18N4O6
- Molecular Weight:302.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) L-Lysine orotate
More- Nature. 2025 Jul;643(8070):192-200. [Abstract]
- Amino Acids. 2024 Sep 18;56(1):56. [Abstract]
- Cell Biochem Biophys. 2025 May 30. [Abstract]
- Vet Microbiol. 2026 May:316:110992. [Abstract]
- iMetaOmics. 2025 Aug 06.
- Patent. US20240216332A1.
- Laurea Magistrale in Biomedical Engineering, Politecnico di Milano. 2019 Jun.
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In Vivo Efficacy Study
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IF
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Cell Migration/Invasion Assay
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WB
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Microbiological Assay
All Endogenous Metabolite Isoforms
More
Biological Activity
Chemical Information
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CAS No. 28003-86-3
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Molecular Weight 302.28
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Formula C11H18N4O6
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SMILES
NCCCC[C@H](N)C(O)=O.OC(C1=CC(NC(N1)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (7)
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Journal Impact Factor
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Most Recent
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Nature
2025 Jul;643(8070):192-200. PMID: 39695227 -
Amino Acids
Identification of amino acids metabolomic profiling in human plasma distinguishes lupus nephritis from systemic lupus erythematosus. [Abstract]2024 Sep 18;56(1):56. PMID: 39292313 -
Cell Biochem Biophys
FOXA1 Transcriptional Repression of PLSCR1 Inhibits Tongue Squamous Cell Carcinoma Progression. [Abstract]2025 May 30. PMID: 40445264 -
Vet Microbiol
The Chinese medicine monomer Schisandrin C inhibits PRRSV infection by regulating the OGT-PI3K/AKT/mTOR signaling pathway. [Abstract]2026 May:316:110992. PMID: 41865607 -
L-Lysine orotate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Serum FITC-dextran levels were reduced upon L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation, indicating improved barrier function. L-Lysine also partially reversed the weight loss.
L-Lysine orotate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Representative immunofluorescence images of ZO-1 and red mean density analysis of ZO-1 in the ileum and colon. L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation significantly restored ZO-1 density.
L-Lysine orotate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Effect of L-Lysine (1.4 mM; 12 h) intervention on the scratch injury healing rate of IFN-γ pre-processed and NCM-460 cells. IFN‐γ significantly impaired healing in NCM-460 cells, and this effect was significantly alleviated by L‐Lysine.
L-Lysine orotate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
Effects of L-Lysine (1.4 mM; 24 h) intervention on the ZO-1 and Occludin expression of IFN-γ pre-processed HIEC-6 cells by western blot.
L-Lysine orotate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.
L-Lysine (0.7-2.8 mM) dose-dependently inhibits H.biformis growth in vitro.
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Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)