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Cat. No.: HY-160735

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L-Phosphinothricin

L-Phosphinothricin is a glutamine synthetase inhibitor and a non-selective herbicide. L-Phosphinothricin acts as a competitive inhibitor, induces toxic ammonium ion accumulation in plants and bacteria, and indirectly blocks the photosynthesis process. L-Phosphinothricin exerts herbicidal activity against both monocotyledonous and dicotyledonous plant species, is primarily absorbed through plant leaves, exhibits limited translocation in plants, and undergoes rapid degradation by soil microorganisms with no root uptake. L-Phosphinothricin can be used for research on weed control in agricultural and non-crop scenarios.

For research use only. We do not sell to patients.

CAS No.: 35597-44-5
Formula: C₅H₁₂NO₄P
Molecular Weight:181.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

L-Phosphinothricin Chemical Structure

CAS No.: 35597-44-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	>500 μM Compound: 3, PT	Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production	[PMID: 17722902]
HEK293	EC₅₀	1100 μM Compound: 3, PT	Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production	[PMID: 17722902]
HEK293	EC₅₀	412 μM Compound: 3, PT	Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production	[PMID: 17722902]

In Vivo

L-Phosphinothricin (150 g a.i./ha; single post-emergence foliar spray) exhibits time-declining control efficacy against Eleusine indica, with a maximum efficacy of 40% at 7 days after application (DAA) and a reduced efficacy of 10% at 28 DAA^[1].
L-Phosphinothricin (150 g a.i./ha; single post-emergence foliar spray) exerts sustained high control against Brachiaria decumbens with 75% efficacy at 7 DAA and 85% efficacy from 14 to 21 DAA, delivers stable high control of Euphorbia heterophylla with a minimum efficacy of 88.8% across 7 to 28 DAA, and achieves potent control of Borreria verticilata with 90% efficacy at 7 DAA and 80% efficacy at 14 DAA^[1].
L-Phosphinothricin (150 g a.i./ha; foliar spray; single application) applied post-emergence provides minimal control of Lolium species^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 35597-44-5
Molecular Weight 181.13
Formula C₅H₁₂NO₄P
SMILES

C([C@@H](C(O)=O)N)CP(C)(=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. LENZ G,et al. An herbicidal combination, composition and method of controlling weeds using the same. WIPO (PCT) Patent WO2024052665A1. 2024-03-14.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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