LC3B recruiter 1
Based on 1 Customer Validation
LC3B recruiter 1 (compound 33R) is an LC3B recruiter fragment. LC3B recruiter 1 directly interacts with LC3B with a KD value of 2.87 µM.
For research use only. We do not sell to patients.
- Purity : 98.76%
- CAS No.: 1281081-32-0
- Formula: C14H10ClN3O2
- Molecular Weight:287.70
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
IC50 & Target
KD: 2.87 µM (LC3B)[1]
Chemical Information
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CAS No. 1281081-32-0
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Appearance Solid
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Molecular Weight 287.70
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Formula C14H10ClN3O2
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Color Off-white to light yellow
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SMILES
O=C(C1=CC=C(Cl)C=C1N2)N(CC3=CC=NC=C3)C2=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (173.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4758 mL | 17.3792 mL | 34.7584 mL | 86.8961 mL |
| 5 mM | 0.6952 mL | 3.4758 mL | 6.9517 mL | 17.3792 mL | |
| 10 mM | 0.3476 mL | 1.7379 mL | 3.4758 mL | 8.6896 mL | |
| 15 mM | 0.2317 mL | 1.1586 mL | 2.3172 mL | 5.7931 mL | |
| 20 mM | 0.1738 mL | 0.8690 mL | 1.7379 mL | 4.3448 mL | |
| 25 mM | 0.1390 mL | 0.6952 mL | 1.3903 mL | 3.4758 mL | |
| 30 mM | 0.1159 mL | 0.5793 mL | 1.1586 mL | 2.8965 mL | |
| 40 mM | 0.0869 mL | 0.4345 mL | 0.8690 mL | 2.1724 mL | |
| 50 mM | 0.0695 mL | 0.3476 mL | 0.6952 mL | 1.7379 mL | |
| 60 mM | 0.0579 mL | 0.2897 mL | 0.5793 mL | 1.4483 mL | |
| 80 mM | 0.0434 mL | 0.2172 mL | 0.4345 mL | 1.0862 mL | |
| 100 mM | 0.0348 mL | 0.1738 mL | 0.3476 mL | 0.8690 mL |