LG-120907
LG-120907 is a selective androgen receptor (AR) antagonist with a Ki value of 26 nM. LG-120907 inhibits Testosterone-induced increases in ventral prostate (VP) tissue weight and seminal vesicles (SV) tissue weight in vivo.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 201654-12-8
- 分子式: C15H13F3N2O
- 分子量:294.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CV-1 | IC50 |
27 nM
Compound: 1
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Antagonist activity at human androgen receptor expressed in CV1 cells
Antagonist activity at human androgen receptor expressed in CV1 cells
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[PMID: 17257838] |
| CV-1 | IC50 |
390 nM
Compound: 36
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Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.
Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.
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[PMID: 9484511] |
| CV-1 | IC50 |
58 nM
Compound: 36
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Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.
Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.
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[PMID: 9484511] |
化学情報
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CAS 番号 201654-12-8
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分子量 294.28
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分子式 C15H13F3N2O
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SMILES
O=C1C=C(C2=CC=3C=CC(NC3C=C2N1)(C)C)C(F)(F)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
LG-120907 関連分類
HY-119436 関連分類
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