Lodenosine
Lodenosine is an active compound.
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- CAS No.: 110143-10-7
- Formule: C10H12FN5O2
- Masse moléculaire:253.23
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| C3H/3T3 | EC50 |
>50 μM
Compound: 2
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Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
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[PMID: 10229630] |
| CCRF-CEM | CC50 |
>250 μM
Compound: 2
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Cytotoxic concentration in Wild Type CEM cells
Cytotoxic concentration in Wild Type CEM cells
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[PMID: 10229630] |
| CCRF-CEM | EC50 |
36.7 μM
Compound: 2
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Antiviral activity evaluated as the ability to inhibit the replication of HIV-1 in human T-lymphocytic cells (CEM)
Antiviral activity evaluated as the ability to inhibit the replication of HIV-1 in human T-lymphocytic cells (CEM)
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[PMID: 10229630] |
| CCRF-CEM | EC50 |
40 μM
Compound: 2
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Antiviral activity evaluated as the ability to inhibit the replication of HIV-2 in human T-lymphocytic cells (CEM)
Antiviral activity evaluated as the ability to inhibit the replication of HIV-2 in human T-lymphocytic cells (CEM)
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[PMID: 10229630] |
| CCRF-CEM | IC50 |
>100 μM
Compound: 15
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Cytotoxicity in CEM cells
Cytotoxicity in CEM cells
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10.1016/0960-894X(95)00133-E |
| H9 | EC50 |
1.16 μM
Compound: beta-FddA
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Antiviral activity against HIV1 3B in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
Antiviral activity against HIV1 3B in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
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[PMID: 11430019] |
| H9 | EC50 |
1.16 μM
Compound: beta-FddA
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Antiviral activity against HIV1 RF in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
Antiviral activity against HIV1 RF in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
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[PMID: 11430019] |
| HepG2 2.2.15 | EC50 |
>10 μM
Compound: 15
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In vitro anti-HBV activity in 2.2.15 cells
In vitro anti-HBV activity in 2.2.15 cells
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10.1016/0960-894X(95)00133-E |
| HepG2 2.2.15 | IC50 |
>200 μM
Compound: 15
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Cytotoxicity in 2.2.15 cells
Cytotoxicity in 2.2.15 cells
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10.1016/0960-894X(95)00133-E |
| MT4 | ED50 |
35 μM
Compound: 11
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Anti-HIV activity was determined as dose required to protect 50% of the HIV-infected MT-4 cells against destruction
Anti-HIV activity was determined as dose required to protect 50% of the HIV-infected MT-4 cells against destruction
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[PMID: 3499515] |
| Vero | IC50 |
>100 μM
Compound: 15
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Cytotoxicity in Vero cells
Cytotoxicity in Vero cells
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10.1016/0960-894X(95)00133-E |
Chemical Information
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CAS No. 110143-10-7
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Masse moléculaire 253.23
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Formule C10H12FN5O2
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SMILES
F[C@@H]1[C@@H](O[C@@H](C1)CO)N2C3=NC=NC(N)=C3N=C2
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Synonyms
NSC 613792; F-ddA
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lodenosine Related Classifications
HY-114887 Related Classifications
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