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  3. Drug Derivative
  4. Lodenosine

Lodenosine is an active compound.

For research use only. We do not sell to patients.

Lodenosine

Lodenosine Chemical Structure

CAS No. : 110143-10-7

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Lodenosine Related Antibodies

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Description

Lodenosine is an active compound.

Cellular Effect
Cell Line Type Value Description References
C3H/3T3 EC50
> 50 μM
Compound: 2
Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
Effect of compound against Moloney murine sarcoma virus (MSV)-induced transformation of C3H/3T3 embryo murine fibroblasts
[PMID: 10229630]
CCRF-CEM CC50
> 250 μM
Compound: 2
Cytotoxic concentration in Wild Type CEM cells
Cytotoxic concentration in Wild Type CEM cells
[PMID: 10229630]
CCRF-CEM EC50
36.7 μM
Compound: 2
Antiviral activity evaluated as the ability to inhibit the replication of HIV-1 in human T-lymphocytic cells (CEM)
Antiviral activity evaluated as the ability to inhibit the replication of HIV-1 in human T-lymphocytic cells (CEM)
[PMID: 10229630]
CCRF-CEM EC50
40 μM
Compound: 2
Antiviral activity evaluated as the ability to inhibit the replication of HIV-2 in human T-lymphocytic cells (CEM)
Antiviral activity evaluated as the ability to inhibit the replication of HIV-2 in human T-lymphocytic cells (CEM)
[PMID: 10229630]
CCRF-CEM IC50
> 100 μM
Compound: 15
Cytotoxicity in CEM cells
Cytotoxicity in CEM cells
10.1016/0960-894X(95)00133-E
H9 EC50
1.16 μM
Compound: beta-FddA
Antiviral activity against HIV1 3B in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
Antiviral activity against HIV1 3B in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
[PMID: 11430019]
H9 EC50
1.16 μM
Compound: beta-FddA
Antiviral activity against HIV1 RF in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
Antiviral activity against HIV1 RF in human H9 cells assessed as inhibition of virus-induced cytopathic effect by formazan-based conventional colorimetric technique
[PMID: 11430019]
HepG2 2.2.15 EC50
> 10 μM
Compound: 15
In vitro anti-HBV activity in 2.2.15 cells
In vitro anti-HBV activity in 2.2.15 cells
10.1016/0960-894X(95)00133-E
HepG2 2.2.15 IC50
> 200 μM
Compound: 15
Cytotoxicity in 2.2.15 cells
Cytotoxicity in 2.2.15 cells
10.1016/0960-894X(95)00133-E
MT4 ED50
35 μM
Compound: 11
Anti-HIV activity was determined as dose required to protect 50% of the HIV-infected MT-4 cells against destruction
Anti-HIV activity was determined as dose required to protect 50% of the HIV-infected MT-4 cells against destruction
[PMID: 3499515]
Vero IC50
> 100 μM
Compound: 15
Cytotoxicity in Vero cells
Cytotoxicity in Vero cells
10.1016/0960-894X(95)00133-E
Molecular Weight

253.23

Formula

C10H12FN5O2
CAS No.
SMILES

F[C@@H]1[C@@H](O[C@@H](C1)CO)N2C3=NC=NC(N)=C3N=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lodenosine Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lodenosine110143-10-7NSC 613792 F-ddANSC613792NSC-613792Drug DerivativeDrug derivativeInhibitorinhibitorinhibit

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