Lonazolac
Based on 1 Customer Validation
Lonazolac is a non-steroidal antirheumatic agent. Anti-inflammatory effects .
For research use only. We do not sell to patients.
- Purity: 99.59%
- CAS No.: 53808-88-1
- Formula: C17H13ClN2O2
- Molecular Weight:312.75
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 53808-88-1
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Appearance Solid
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Molecular Weight 312.75
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Formula C17H13ClN2O2
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Color Light yellow to yellow
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SMILES
O=C(O)CC1=CN(C2=CC=CC=C2)N=C1C3=CC=C(Cl)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 125 mg/mL (399.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Trnavský K, et al. [Lonazolac - a new non-steroidal antirheumatic agent. Report of a double-blind crossover clinical study]. Fysiatr Revmatol Vestn. 1983;61(3):147-152. [Content Brief]
[2]. Harras MF, et al. Discovery of new non-acidic lonazolac analogues with COX-2 selectivity as potent anti-inflammatory agents. Medchemcomm. 2019;10(10):1775-1788. Published 2019 Jul 22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1974 mL | 15.9872 mL | 31.9744 mL | 79.9361 mL |
| 5 mM | 0.6395 mL | 3.1974 mL | 6.3949 mL | 15.9872 mL | |
| 10 mM | 0.3197 mL | 1.5987 mL | 3.1974 mL | 7.9936 mL | |
| 15 mM | 0.2132 mL | 1.0658 mL | 2.1316 mL | 5.3291 mL | |
| 20 mM | 0.1599 mL | 0.7994 mL | 1.5987 mL | 3.9968 mL | |
| 25 mM | 0.1279 mL | 0.6395 mL | 1.2790 mL | 3.1974 mL | |
| 30 mM | 0.1066 mL | 0.5329 mL | 1.0658 mL | 2.6645 mL | |
| 40 mM | 0.0799 mL | 0.3997 mL | 0.7994 mL | 1.9984 mL | |
| 50 mM | 0.0639 mL | 0.3197 mL | 0.6395 mL | 1.5987 mL | |
| 60 mM | 0.0533 mL | 0.2665 mL | 0.5329 mL | 1.3323 mL | |
| 80 mM | 0.0400 mL | 0.1998 mL | 0.3997 mL | 0.9992 mL | |
| 100 mM | 0.0320 mL | 0.1599 mL | 0.3197 mL | 0.7994 mL |
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