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Cat. No.: HY-173466

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LT-188A

LT-188A is a potent TGR5 agonist with an EC₅₀ of 23 μM. LT-188A decreases the levels of inflammatory mediators in macrophages.

For research use only. We do not sell to patients.

CAS No.: 2922530-99-0
Formula: C₂₈H₃₆O₇
Molecular Weight:484.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

LT-188A Chemical Structure

CAS No.: 2922530-99-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

LT-188A is a potent TGR5 agonist with an EC₅₀ of 23 μM. LT-188A decreases the levels of inflammatory mediators in macrophages^[1].

Chemical Information

CAS No. 2922530-99-0
Molecular Weight 484.58
Formula C₂₈H₃₆O₇
SMILES

COC1=C(OC)C=C(C[C@H]2CO[C@H](C3=CC(OC)=C(OC)C=C3)[C@H]2CCOC(/C(C)=C\C)=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Perhal AF, et al. dentification and Characterization of a Leoligin-Inspired Synthetic Lignan as a TGR5 Agonist. J Nat Prod. 2025 Apr 25;88(4):985-995. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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