1. GPCR/G Protein
  2. Leukotriene Receptor
  3. LTB4 antagonist 2

LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM.

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LTB4 antagonist 2 Chemical Structure

LTB4 antagonist 2 Chemical Structure

CAS No. : 2929239-85-8

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Description

LTB4 antagonist 2, a carboxamide-acid compound, is an antagonist of leukotriene B4 (LTB4) with potentially anti-inflammatory activity. LTB4 antagonist 2 shows good affinity for the LTB4 receptor with IC50 of 439 nM[1].

IC50 & Target[1]

LTB4

439 nM (IC50)

In Vitro

LTB4 antagonist 2 (compound 24c) (0.1 μM, 10 μM) shows the inhibition of specific binding LTB4, with 25% and 95% inhibitory rates at 0.1 μM and 10 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

445.46

Formula

C26H23NO6

CAS No.
SMILES

CN(C(C1=C(OC2=CC=C(C=C2O1)OCC3=CC=CC=C3)C(O)=O)=O)CCC4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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LTB4 antagonist 2 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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LTB4 antagonist 2
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HY-149083
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