LY309887 (Standard)
LY309887 (Standard) is the analytical standard of LY309887 (HY-10818). This product is intended for research and analytical applications. LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity.
For research use only. We do not sell to patients.
- CAS No.: 127228-54-0
- Formula: C19H23N5O6S
- Molecular Weight:449.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Ki: 6.5 nM (GARFT), 1.78 nM (Folate receptor α), 18.2 nM (Folate receptor β)[1]
Chemical Information
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CAS No. 127228-54-0
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Molecular Weight 449.48
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Formula C19H23N5O6S
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SMILES
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(CC[C@@H](CN2)CC3=C2N=C(N)NC3=O)S1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)