M 16209
M 16209 is an orally active aldose reductase (AR) inhibitor. M 16209 inhibits partially purified AR from various sources with IC50 values of 0.12, 0.24, 4.5, 1.2 and 9.3 μM for rat lens AR, bovine lens AR, bovine kidney AR, canine lens AR and human placental AR. M 16209 can be used for the research of metabolic disease, such as diabetes.
For research use only. We do not sell to patients.
- CAS No.: 128851-36-5
- Formula: C11H7BrN2O5S
- Molecular Weight:359.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
M 16209 (10-30 mg/kg, p.o., daily for 14 days) ameliorates motor nerve conduction velocity delay in male Wistar rats with Streptozotocin (HY-13753)-induced diabetic neuropathy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 128851-36-5
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Molecular Weight 359.15
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Formula C11H7BrN2O5S
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SMILES
O=C1NC(CN1S(=O)(C2=C(Br)C3=CC=CC=C3O2)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
M 16209 Related Classifications
HY-101555 Related Classifications
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