m-Iodobenzylguanidine
Based on 1 publication(s) in Google Scholar
m-Iodobenzylguanidine (Iobenguane) is a ligand with high affinity against norepinephrine transporter (NET). m-Iodobenzylguanidine is used as an imaging agent in the diagnostic imaging and radionuclide studies of neuroendocrine tumors, such as neuroblastoma, pheochromocytoma and carcinoid tumor.
For research use only. We do not sell to patients.
- Purity: ≥97.0%
- CAS No.: 80663-95-2
- Formula: C8H10IN3
- Molecular Weight:275.09
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications Citing Use of MedChemExpress (MCE) m-Iodobenzylguanidine
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Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 80663-95-2
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Appearance Solid
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Molecular Weight 275.09
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Formula C8H10IN3
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SMILES
IC1=CC=CC(=C1)CNC(=N)N
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Synonyms
MIBG; Iobenguane
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2024 Sep;633(8029):473-479. PMID: 39143211
Solvent & Solubility
DMSO : 100 mg/mL (363.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6352 mL | 18.1759 mL | 36.3517 mL | 90.8793 mL |
| 5 mM | 0.7270 mL | 3.6352 mL | 7.2703 mL | 18.1759 mL | |
| 10 mM | 0.3635 mL | 1.8176 mL | 3.6352 mL | 9.0879 mL | |
| 15 mM | 0.2423 mL | 1.2117 mL | 2.4234 mL | 6.0586 mL | |
| 20 mM | 0.1818 mL | 0.9088 mL | 1.8176 mL | 4.5440 mL | |
| 25 mM | 0.1454 mL | 0.7270 mL | 1.4541 mL | 3.6352 mL | |
| 30 mM | 0.1212 mL | 0.6059 mL | 1.2117 mL | 3.0293 mL | |
| 40 mM | 0.0909 mL | 0.4544 mL | 0.9088 mL | 2.2720 mL | |
| 50 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8176 mL | |
| 60 mM | 0.0606 mL | 0.3029 mL | 0.6059 mL | 1.5147 mL | |
| 80 mM | 0.0454 mL | 0.2272 mL | 0.4544 mL | 1.1360 mL | |
| 100 mM | 0.0364 mL | 0.1818 mL | 0.3635 mL | 0.9088 mL |