2. Membrane Transporter/Ion Channel
  3. Monoamine Transporter
  4. m-Iodobenzylguanidine

m-Iodobenzylguanidine  (Synonyms: MIBG; Iobenguane)

Cat. No.: HY-129040 Purity: ≥97.0%
COA
SDS
Handling Instructions Technical Support

m-Iodobenzylguanidine (Iobenguane) is a ligand with high affinity against norepinephrine transporter (NET). m-Iodobenzylguanidine is used as an imaging agent in the diagnostic imaging and radionuclide studies of neuroendocrine tumors, such as neuroblastoma, pheochromocytoma and carcinoid tumor.

For research use only. We do not sell to patients.

m-Iodobenzylguanidine

m-Iodobenzylguanidine Chemical Structure

CAS No. : 80663-95-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Based on 1 publication(s) in Google Scholar

Other Forms of m-Iodobenzylguanidine:

m-Iodobenzylguanidine Related Antibodies

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1 Publications Citing Use of MCE m-Iodobenzylguanidine

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  • Purity & Documentation

  • References

  • Customer Review

Description

m-Iodobenzylguanidine (Iobenguane) is a ligand with high affinity against norepinephrine transporter (NET). m-Iodobenzylguanidine is used as an imaging agent in the diagnostic imaging and radionuclide studies of neuroendocrine tumors, such as neuroblastoma, pheochromocytoma and carcinoid tumor[1].

Clinical Trial
Molecular Weight

275.09

Formula

C8H10IN3
CAS No.
Appearance

Solid

SMILES

IC1=CC=CC(=C1)CNC(=N)N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (363.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6352 mL 18.1759 mL 36.3517 mL
5 mM 0.7270 mL 3.6352 mL 7.2703 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥97.0%

SDS (393 KB)

COA (244 KB) HNMR (117 KB) LCMS (326 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6352 mL 18.1759 mL 36.3517 mL 90.8793 mL
5 mM 0.7270 mL 3.6352 mL 7.2703 mL 18.1759 mL
10 mM 0.3635 mL 1.8176 mL 3.6352 mL 9.0879 mL
15 mM 0.2423 mL 1.2117 mL 2.4234 mL 6.0586 mL
20 mM 0.1818 mL 0.9088 mL 1.8176 mL 4.5440 mL
25 mM 0.1454 mL 0.7270 mL 1.4541 mL 3.6352 mL
30 mM 0.1212 mL 0.6059 mL 1.2117 mL 3.0293 mL
40 mM 0.0909 mL 0.4544 mL 0.9088 mL 2.2720 mL
50 mM 0.0727 mL 0.3635 mL 0.7270 mL 1.8176 mL
60 mM 0.0606 mL 0.3029 mL 0.6059 mL 1.5147 mL
80 mM 0.0454 mL 0.2272 mL 0.4544 mL 1.1360 mL
100 mM 0.0364 mL 0.1818 mL 0.3635 mL 0.9088 mL
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m-Iodobenzylguanidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

m-Iodobenzylguanidine80663-95-2MIBG IobenguaneMonoamine TransporterNET Ligandnorepinephrine transporter neuroblastomapheochromocytoma and carcinoid tumorInhibitorinhibitorinhibit

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