m7Gpppm6AmpG ammonium solution (100 mM)

Cat. No.: HY-145975A Purity: 98.26%: Data Sheet
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m7Gpppm6AmpG ammonium solution (100 mM) is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro.

For research use only. We do not sell to patients.

m7Gpppm6AmpG ammonium solution (100 mM) Chemical Structure

Size	Stock	Quantity
Solvent
1.2 mg (100 mM * 10 μL in Water)	In-stock	Estimated Time of Arrival: December 31
Solvent
5.8 mg (100 mM * 50 μL in Water)	In-stock	Estimated Time of Arrival: December 31
Solvent
11.6 mg (100 mM * 100 μL in Water)	In-stock	Estimated Time of Arrival: December 31

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Description	m7Gpppm6AmpG ammonium solution (100 mM) is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro^[1].
Molecular Weight	1159.69 (free acid)
Formula	C₃₃H₄₅N₁₅O₂₄P₄.xNH₃
Appearance	Liquid
Color	Colorless to light yellow
SMILES	O=P(O)(OC[C@@H]1[C@@H](OP(O)(OC[C@H]2O[C@@H](N3C(NC(N)=NC4=O)=C4N=C3)[C@H](O)[C@@H]2O)=O)[C@@H](OC)[C@H](N5C6=NC=NC(NC)=C6N=C5)O1)OP(OP(OC[C@H]7O[C@@H](N8C(NC(N)=N9)=C([N+](C)=C8)C9=O)[C@H](O)[C@@H]7O)([O-])=O)(O)=O.[xNH3]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Solution, -20°C, 2 years
Purity & Documentation	Purity: 98.26% Select Batch: Data Sheet (276 KB) SDS (252 KB) COA (263 KB) HNMR (301 KB) RP-HPLC (242 KB) MS (217 KB) Handling Instructions (2659 KB)
References	[1]. Sikorski PJ, Warminski M, Kubacka D, et al. The identity and methylation status of the first transcribed nucleotide in eukaryotic mRNA 5' cap modulates protein expression in living cells. Nucleic Acids Res. 2020;48(4):1607-1626. [Content Brief]

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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m7Gpppm6AmpG ammonium solution (100 mM)DNA/RNA SynthesisRNA synthesisInhibitorinhibitorinhibit

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m7Gpppm6AmpG ammonium solution (100 mM)

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