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Cat. No.: HY-162304

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MAGL-IN-14

MAGL-IN-14 (compound 2) is a potent inhibitor of MAGL, with IC₅₀ of 0.00289 μM and 0.002 μM in HEK293 and PC3 cells, respectively.

For research use only. We do not sell to patients.

CAS No.: 2770967-04-7
Formula: C₁₇H₁₇F₆N₃O₃
Molecular Weight:425.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

MAGL-IN-14 Chemical Structure

CAS No.: 2770967-04-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MAGL-IN-14 (compound 2) is a potent inhibitor of MAGL, with IC₅₀ of 0.00289 μM and 0.002 μM in HEK293 and PC3 cells, respectively^[1].

Chemical Information

CAS No. 2770967-04-7
Molecular Weight 425.33
Formula C₁₇H₁₇F₆N₃O₃
SMILES

O=C([C@H]1CC12CCN(C(OC(C(F)(F)F)C(F)(F)F)=O)CC2)NC3=CC=CN=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. H. Lundbeck A/S. Preparation of ubstituted 1,1,1,3,3,3-hexafluoropropan-2-yl 6-azaspiro[2.5]octane-6-carboxylates as MAGL inhibitors. World Intellectual Property Organization, WO2022101412 A1 2022-05-19.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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