2. Metabolic Enzyme/Protease
  3. Mitochondrial Metabolism
  4. Malonyl CoA lithium

Malonyl CoA lithium  (Synonyms: Malonyl coenzyme A lithium)

Cat. No.: HY-136408 Purity: ≥90.0%
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Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation.

For research use only. We do not sell to patients.

Malonyl CoA lithium Chemical Structure

Malonyl CoA lithium Chemical Structure

CAS No. : 108347-84-8

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Based on 1 publication(s) in Google Scholar

Other Forms of Malonyl CoA lithium:

Malonyl CoA lithium Related Antibodies

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Description

Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation[1].

IC50 & Target

Carnitine palmitoyl transferase 1 (CPT1)[1]
In Vitro

Incubation of myotubes with Malonyl CoA lithium (with a polyamine carrier) prevents insulin-stimulated glucose transport and inhibits palmitate oxidation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Malonyl CoA lithium Related Antibodies

Cell Viability Assay[1]

Cell Line: Myotubes
Concentration: 10 μM
Incubation Time: 30 min
Result: Prevented insulin-stimulated glucose transport and inhibited palmitate oxidation.
Formula

C24H38N7O19P3S.xLi
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]1O[P](O)(O)=O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CC(O)=O)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2.[Li]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

PBS : 10 mg/mL (adjust pH to 7.2)

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Purity & Documentation

Purity: ≥90.0%

COA (245 KB)

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Malonyl CoA lithium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Malonyl CoA108347-84-8Malonyl coenzyme AMitochondrial Metabolismfatty acidoxidationCPT1carnitine palmitoyl transferase 1Inhibitorinhibitorinhibit

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