1. Neuronal Signaling
  2. Monoamine Oxidase
    Amyloid-β
  3. MAO-B-IN-10

MAO-B-IN-10 

Cat. No.: HY-146347
Handling Instructions

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research.

For research use only. We do not sell to patients.

MAO-B-IN-10 Chemical Structure

MAO-B-IN-10 Chemical Structure

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Description

MAO-B-IN-10 (compound 4f) is a potent, selective, BBB-penetrated MAO-B (monoamine oxidase-B) inhibitor, with IC50 of 5.3 μM. MAO-B-IN-10 can inhibit (58.2%) and disaggregate (43.3%) self-mediated Aβ (amyloid β) aggregation. MAO-B-IN-10 can be use for Alzheimer’s disease research[1].

IC50 & Target

MAO-B

5.3 ± 0.22 μM (IC50)

MAO-A

15.9 ± 0.1 μM (IC50)

Molecular Weight

394.46

Formula

C23H26N2O4

SMILES

CCN(C(OC1=C(C=C(C=C1)/C=C/C(N2CCC3=C(C2)C=CC=C3)=O)OC)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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MAO-B-IN-10
Cat. No.:
HY-146347
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