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Cat. No.: HY-168307

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Me-Thalidomide-O-C8-NH2

Me-Thalidomide-O-C8-NH2 is an E3 ligase ligand-linker conjugate. Me-Thalidomide-O-C8-NH2 can be used in the synthesis of MS154N (HY-157579).

For research use only. We do not sell to patients.

CAS No.: 2550393-20-7
Formula: C₂₂H₂₉N₃O₅
Molecular Weight:415.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Me-Thalidomide-O-C8-NH2 Chemical Structure

CAS No.: 2550393-20-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Me-Thalidomide-O-C8-NH2 is an E3 ligase ligand-linker conjugate. Me-Thalidomide-O-C8-NH2 can be used in the synthesis of MS154N (HY-157579)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2550393-20-7
Molecular Weight 415.48
Formula C₂₂H₂₉N₃O₅
SMILES

NCCCCCCCCOC1=CC=CC(C2=O)=C1C(N2C3C(N(C)C(CC3)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cheng M, et al. Discovery of potent and selective epidermal growth factor receptor (EGFR) bifunctional small-molecule degraders[J]. Journal of medicinal chemistry, 2020, 63(3): 1216-1232. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Me-Thalidomide-O-C8-NH2

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Me-Thalidomide-O-C8-NH2 Related Classifications

HY-168307 Related Classifications