Merenskine
Merenskine is a chlorinated 1,2-unsaturated senecionine-type pyrrolizidine alkaloid and serves as a substrate for epoxidation reactions. Merenskine forms merepoxine N-oxide upon evaporation in ammoniated solvents, while it generates merepoxine under alkaline sample preparation conditions. Merenskine exhibits a pH-dependent transfer rate in black tea infusion, and the transfer rate decreases sharply under alkaline conditions.
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- CAS No.: 96657-94-2
- Formula: C18H26ClNO6
- Molecular Weight:387.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
Merenskine (5-100 μg/mL) and its N-oxide are pyrrolizidine alkaloids not naturally present in Jacobaea species[1].
Merenskine undergoes significant degradation (up to 99% loss) when brewed in alkaline (pH 9) tea infusion conditions, alongside Jaconine and Merenskine N-oxide[2].
Merenskine (2.5 ng/mL; 5 min) exhibits pH-dependent transfer from fortified black tea to infusions, with transfer rates dropping to 2% at pH 9[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 96657-94-2
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Molecular Weight 387.86
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Formula C18H26ClNO6
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SMILES
O=C(OC(CC1)[C@]2([H])N1CC=C2CO3)[C@@](O)(CCl)[C@H](C)[C@@H](C)[C@](O)(C)C3=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)