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Cat. No.: HY-182425

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MI-23

MI-23 is a SARS-CoV-2 main protease (SARS-CoV-2 M_pro) inhibitor with an IC₅₀ of 7.6 nM. MI-23 is applicable to the research of COVID-19.

For research use only. We do not sell to patients.

CAS No.: 2698348-90-0
Formula: C₂₄H₂₉F₂N₃O₄
Molecular Weight:461.50

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

MI-23 Chemical Structure

CAS No.: 2698348-90-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MI-23 is a SARS-CoV-2 main protease (SARS-CoV-2 M_pro) inhibitor with an IC₅₀ of 7.6 nM. MI-23 is applicable to the research of COVID-19^[1].

Chemical Information

CAS No. 2698348-90-0
Molecular Weight 461.50
Formula C₂₄H₂₉F₂N₃O₄
SMILES

O=C(NCC1)[C@@H]1C[C@@H](C=O)NC([C@@H]2[C@]3([H])[C@](CCC3)([H])CN2C(CCC4=CC(F)=CC(F)=C4)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Qiao J, et al. SARS-CoV-2 M^pro inhibitors with antiviral activity in a transgenic mouse model. Science. 2021;371(6536):1374-1378. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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