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Cat. No.: HY-N10796

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Miltipolone

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Miltipolone is a potent cytotoxic compound isolated from the fresh roots of Salvia divinorum.

For research use only. We do not sell to patients.

Purity: 95.36%
CAS No.: 131086-61-8
Formula: C₁₉H₂₄O₃
Molecular Weight:300.39

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Miltipolone Chemical Structure

CAS No.: 131086-61-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Miltipolone is a potent cytotoxic compound isolated from the fresh roots of Salvia divinorum^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A-375	IC₅₀	3.5 μM Compound: 1, CCDC759536	Antiproliferative activity against human A375 cells after 96 hrs by MTT assay Antiproliferative activity against human A375 cells after 96 hrs by MTT assay	[PMID: 21296467]
A549	IC₅₀	1.92 μM Compound: 1, CCDC759536	Antiproliferative activity against human A549 cells after 96 hrs by MTT assay Antiproliferative activity against human A549 cells after 96 hrs by MTT assay	[PMID: 21296467]
Bel-7402	IC₅₀	0.9 μM Compound: 1, CCDC759536	Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 96 hrs by MTT assay	[PMID: 21296467]
HeLa	IC₅₀	1.44 μM Compound: 1, CCDC759536	Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay Antiproliferative activity against human HeLa cells after 96 hrs by MTT assay	[PMID: 21296467]
HepG2	IC₅₀	2 μM Compound: 1, CCDC759536	Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 21296467]
HT-1080	IC₅₀	1.36 μM Compound: 1, CCDC759536	Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 96 hrs by MTT assay	[PMID: 21296467]
HUVEC	IC₅₀	20 μM Compound: 1, CCDC759536	Antiproliferative activity against human HUVEC cells after 96 hrs by MTT assay Antiproliferative activity against human HUVEC cells after 96 hrs by MTT assay	[PMID: 21296467]
Jurkat	IC₅₀	1.4 μM Compound: 1, CCDC759536	Antiproliferative activity against human Jurkat cells after 96 hrs by MTT assay Antiproliferative activity against human Jurkat cells after 96 hrs by MTT assay	[PMID: 21296467]
MCF7	IC₅₀	2 μM Compound: 1, CCDC759536	Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 21296467]
NCI-N87	IC₅₀	1.6 μM Compound: 1, CCDC759536	Antiproliferative activity against human NCI-N87 cells after 96 hrs by MTT assay Antiproliferative activity against human NCI-N87 cells after 96 hrs by MTT assay	[PMID: 21296467]
PANC-1	IC₅₀	5.95 μM Compound: 1, CCDC759536	Antiproliferative activity against human PANC1 cells after 96 hrs by MTT assay Antiproliferative activity against human PANC1 cells after 96 hrs by MTT assay	[PMID: 21296467]

Chemical Information

CAS No. 131086-61-8
Appearance Solid
Molecular Weight 300.39
Formula C₁₉H₂₄O₃
Color Yellow to brown
SMILES

O=C1C=C2C([C@@H]3CC4C(C)(C)CCC[C@]24CO3)=CC(C)=C1O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Plants
- Chenopodiaceae
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Haro Ginda, et al. Miltipolone, a New Diterpenoid Tropolone Possessing Cytotoxic Activities from Salvia miltiorrhiza Bunge. Chemistry Letters 1990, Vol.19, No.9.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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