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  3. Mito-PN

Mito-PN is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

For research use only. We do not sell to patients.

Mito-PN Chemical Structure

Mito-PN Chemical Structure

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Description

Mito-PN is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

In Vitro

In the fluorescence spectra, the solution of free probe Mito-PN (5 μM) displays a negligible fluorescence emission in the aqueous solution containing phosphate buffered solution (PBS, 20 mM, pH = 7.4). The non-fluorescence property of probe Mito-PN might be ascribed to the inherent structure of a spirolactone. As expected, the considerable fluorescence enhancement (about 40-fold) at 630 nm was observed upon addition of ONOO. Surprisingly, a fast response of probe Mito-PN for detecting ONOO (<5 s) was achieved, and this feature is advantageous than the reported conjugation of rhodamine and phenylhydrazine (the complete reaction needs about 1 h). The fast response enables probe Mito-PN convenient to track the highly reactive and short-lived ONOO in the biological systems. Meanwhile, the absorption spectral properties of probe Mito-PN were also investigated. Probe Mito-PN exhibited an obvious increase at about 570 nm upon addition of ONOO[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

451.52

Formula

C28H25N3O3

Unlabeled CAS

SMILES

OC1=CC(C=C2)=C(C=C1)C3=C2C(C4=CC=CC=C4C5=O)(N5N)C6=C(O3)C=C(N(CC)CC)C=C6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mito-PN
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HY-D1150
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