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Cat. No.: HY-116508

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MK 319

MK 319 is a selective aldose reductase (AR) inhibitor with an IC₅₀ of 0.3 μM. MK 319 can be utilized in diabetes research.

For research use only. We do not sell to patients.

CAS No.: 1462383-00-1
Formula: C₁₆H₉BrClF₄NO₄
Molecular Weight:470.60

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

MK 319 Chemical Structure

CAS No.: 1462383-00-1

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

MK 319 is a selective aldose reductase (AR) inhibitor with an IC₅₀ of 0.3 μM. MK 319 can be utilized in diabetes research^[1].

Chemical Information

CAS No. 1462383-00-1
Molecular Weight 470.60
Formula C₁₆H₉BrClF₄NO₄
SMILES

O=C(C1=CC=C(C=C1OCC(O)=O)Cl)NCC2=C(C(F)=C(C(F)=C2F)Br)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cousido-Siah A, et al. IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. ACS Chem Biol. 2016 Oct 21;11(10):2693-2705. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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