ML3403
Based on 1 Customer Validation
ML3403 is a potent p38 MAPK inhibitor with an IC50 of 0.38 μM.
For research use only. We do not sell to patients.
- Purity: 99.28%
- CAS No.: 549505-65-9
- Formula: C23H21FN4S
- Molecular Weight:404.50
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
160 nM
Compound: k00568a, ML3403
|
Inhibition of LPS-stimulated TNFalpha release in human PBMC
Inhibition of LPS-stimulated TNFalpha release in human PBMC
|
[PMID: 18077363] |
| PBMC | IC50 |
39 nM
Compound: k00568a, ML3403
|
Inhibition of LPS-stimulated IL1 release in human PBMC
Inhibition of LPS-stimulated IL1 release in human PBMC
|
[PMID: 18077363] |
Chemical Information
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CAS No. 549505-65-9
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Appearance Solid
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Molecular Weight 404.50
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Formula C23H21FN4S
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Color White to off-white
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SMILES
CC(NC1=NC=CC(C2=C(C3=CC=C(F)C=C3)N=C(SC)N2)=C1)C4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)