Moscatin
Moscatin inhibits AA-induced platelet aggregation in a concentration-dependent manner with IC50 values 37.2 μM .
For research use only. We do not sell to patients.
- CAS No.: 108335-06-4
- Formula: C15H12O3
- Molecular Weight:240.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 13
|
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
|
[PMID: 27310249] |
| HeLa | IC50 |
>10 μM
Compound: 13
|
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
|
[PMID: 27310249] |
| HL-60 | IC50 |
19.15 μM
Compound: Moscatin
|
Cytotoxicity against human HL60 cells after 48 to 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 48 to 72 hrs by MTT assay
|
[PMID: 30684866] |
| MCF7 | IC50 |
>10 μM
Compound: 13
|
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
|
[PMID: 27310249] |
| Platelet | IC50 |
37.2 μM
Compound: 2
|
Antiplatelet activity against washed rabbit platelet assessed as inhibition of arachidonic acid-induced platelet aggregation preincubated for 3 mins by turbidimetric method
Antiplatelet activity against washed rabbit platelet assessed as inhibition of arachidonic acid-induced platelet aggregation preincubated for 3 mins by turbidimetric method
|
[PMID: 7798962] |
Chemical Information
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CAS No. 108335-06-4
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Molecular Weight 240.25
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Formula C15H12O3
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SMILES
OC1=CC(OC)=C2C3=C(O)C=CC=C3C=CC2=C1
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Synonyms
Plicatol B
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)