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Cat. No.: HY-B1584R

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Captan (Standard)

Captan (Standard) is the analytical standard of Captan (HY-B1584). This product is intended for research and analytical applications. Captan is a thiol-reactive fungicide. Captan irreversibly depletes protein and non-protein thiols (including glutathione), reducing enzyme activity and fungal respiration/metabolism. Captan inhibits DNA synthesis and replication fork progression, and induces ROS accumulation, oxidative stress, inflammation, ER stress, mitochondrial dysfunction, autophagy, DNA damage, and apoptosis as well as loss of membrane integrity with necrosis. Captan is used to control fungal diseases of various fruits, vegetables, and ornamental plants.

For research use only. We do not sell to patients.

CAS No.: 133-06-2
Formula: C₉H₈Cl₃NO₂S
Molecular Weight:300.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Captan (Standard) Chemical Structure

CAS No.: 133-06-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 133-06-2
Molecular Weight 300.59
Formula C₉H₈Cl₃NO₂S
SMILES

O=C1N(SC(Cl)(Cl)Cl)C(C2CC=CCC12)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Scariot FJ, et al. Necrotic and apoptotic cell death induced by Captan on Saccharomyces cerevisiae. World journal of microbiology & biotechnology. 2017 Aug;33(8):159.

[2]. Fernandez-Vidal A, et al. Exposure to the Fungicide Captan Induces DNA Base Alterations and Replicative Stress in Mammalian Cells. Environmental and molecular mutagenesis. 2019 Apr;60(3):286-297.

[3]. He QK, et al. Captan exposure disrupts ovarian homeostasis and affects oocytes quality via mitochondrial dysfunction induced apoptosis. Chemosphere. 2022 Jan;286(Pt 1):131625.

[4]. Inoue T, et al. Captan-induced increase in the concentrations of intracellular Ca2+ and Zn2+ and its correlation with oxidative stress in rat thymic lymphocytes. Environ Toxicol Pharmacol. 2018 Oct;63:78-83.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Captan (Standard)

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