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Cat. No.: HY-W716865

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CBNQ

(Synonyms: Cannabinolquinone; HU-345)

CBNQ (Compound 22; Cannabinolquinone; HU-345) is an oxidative product of cannabinol.

For research use only. We do not sell to patients.

CAS No.: 731773-46-9
Formula: C₂₁H₂₄O₃
Molecular Weight:324.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

CBNQ Chemical Structure

CAS No.: 731773-46-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

CBNQ (Compound 22; Cannabinolquinone; HU-345) is an oxidative product of cannabinol^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BT-549	IC₅₀	6.05 μg/mL Compound: 10	Anticancer activity against human BT549 cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay Anticancer activity against human BT549 cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay	[PMID: 29232588]
HEK-293T	EC₅₀	23.1 μM Compound: 22; CBNQ	Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay	[PMID: 32315173]
LLC-PK1	IC₅₀	5.65 μg/mL Compound: 10	Cytotoxicity against pig LLC-PK1 cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay Cytotoxicity against pig LLC-PK1 cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay	[PMID: 29232588]
SK-MEL	IC₅₀	7.6 μg/mL Compound: 10	Anticancer activity against human SK-MEL cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay Anticancer activity against human SK-MEL cells assessed as cell growth inhibition incubated for 48 hrs by neutral red dye based assay	[PMID: 29232588]

Chemical Information

CAS No. 731773-46-9
Molecular Weight 324.41
Formula C₂₁H₂₄O₃
SMILES

O=C1C=C(CCCCC)C(C2=C1C3=C(C=CC(C)=C3)C(C)(C)O2)=O
Synonyms

Cannabinolquinone; HU-345
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Caprioglio D, et al. The Oxidation of Phytocannabinoids to Cannabinoquinoids. J Nat Prod. 2020 May 22;83(5):1711-1715. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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